|Issuer:||ITEOS THERAPEUTICS, INC. (ITOS)|
|Original Submission Date:|
C/O ITEOS THERAPEUTICS, INC.
139 MAIN STREET CAMBRIDGE, MA 02142
|Title of Security||Transaction Date||2a. Deemed Execution Date||Transaction Code||Shares||Acquired or Disposed||Price per share||5. Amount of Securities Beneficially Owned Following Reported Transaction||6. Ownership Form Direct or Indirect||Nature of Indirect Ownership|
|Title of Derivative Security||Conversion or Exercise Price of Derivative Security||Transaction Date||Deemed Execution Date||Transaction Code||Number of Derivative Securities Acquired (A) or Disposed of (D)||Date Exercisable||Expiration Date||Title and Amount of Securities Underlying Derivative Security||Price of Derivative Security||Number of derivative Securities Beneficially Owned Following Reported Transaction(s)||Ownership Form: Direct (D) or Indirect (I)||Nature of Indirect Beneficial Ownership|
|STOCK OPTION (RIGHT TO BUY)||41.58||2021-03-01||deemed execution date||A||72,000 (a)||2031-03-01||common stock 72,000||$41.58||72,000||direct|
|f1||this stock option shall vest over 4 years, with 25% vesting on march 1, 2022 and thereafter in equal monthly installments over the next 36 months subject to the reporting person's continued service to the issuer.|